کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5285753 1385765 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A convenient semicarbazide resin for the solid-phase synthesis of peptide ketones and aldehydes
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
A convenient semicarbazide resin for the solid-phase synthesis of peptide ketones and aldehydes
چکیده انگلیسی
Use of a semicarbazide resin for the solid-phase preparation of peptide ketones and aldehydes led to optimal results in terms of both purity of the final product and overall yield. The resin was prepared without complication by activation of the commercially available aminomethyl polystyrene with CDI at room temperature, followed by treatment with tert-butyl carbazate. Furthermore, the TNBSA colorimetric assay has been adapted for checking the incorporation of the carbonyl moiety onto hydrazine-based resins.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 47, Issue 10, 6 March 2006, Pages 1657-1661
نویسندگان
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