Hydrogenolysis of O-protected hydroxyoxetanes over palladium: An efficient method for a one-step ring opening and detritylation reaction

An efficient method for the palladium mediated hydrogenation of an optically active, O-protected hydroxyoxetane derivative has been developed. Using appropriate solvents, in a one-step reaction, optically active 1,4-diol was formed over a Pd/C catalyst, during hydrogenolytic ring opening and detritylation reactions.