Electronic structure analysis of isomeric preferences of canonical and zwitterionic forms of lornoxicam

- Conformational analysis of isomeric and zwitterionic forms.
- Existence of resonance assisted hydrogen bonding (RAHB).
- Effect of dielectric constants on the thermodynamic stabilities of canonical and zwitterionic forms.
- Explicit water mediated stabilization of zwitterion.
- Microsolavtion analysis and elucidation of pathway for the conversion of canonical to zwitterionic form.