Synthesis of Mn-modified CdTe nanoparticles and their application as fluorescence probe

Mn-modified CdTe nanoparticles (NPs) were synthesized via a novel, facile method at low temperature. The modified NPs were directly synthesized in aqueous solution by mixing CdCl2·2.5H2O, fresh NaHTe solution, thioglycolic acid (TGA) and MnCl2·4H2O under suitable conditions. Mn-modified CdTe NPs were evaluated as fluorescence probe for bovine serum albumin (BSA) in aqueous solution. Experiment results showed that the fluorescence emission of Mn-modified CdTe NPs was enhanced significantly by BSA, while other substances exhibited no significant effect on NPs. Under the optimal conditions, the response was linearly proportional to the concentration of BSA ranging from 5.0×10−9 to 7.0×10−7 mol/L with detection limit 5.26×10−10 mol/L. Based on the distinct optical properties of Mn-modified CdTe NPs with BSA, Mn-modified CdTe NPs can be developed as a potential identified fluorescence probe for BSA in aqueous solution.