Spectroscopic studies on the interaction between ZnSe nanoparticles with bovine serum albumin

►Interaction between bovine serum albumin (BSA) and ZnSe nanoparticles was studied. ► UV-vis data and fluorescence data demonstrated the formation of ZnSe-BSA complex. ► Temperature dependence of ZnSe-BSA emission was sensitive to the conformational changes of protein.