Determination of rifampicin based on fluorescence quenching of GSH capped CdTe/ZnS QDs

► Fluorescence of CdTe/ZnS QDs was found to be quenched notably by rifampicin. ► A simple, rapid and sensitive fluorimetric method for the determination of Rfp was developed. ► Interaction mechanism of CdTe/ZnS QDs with rifampicin was investigated. ► Proposed method was applied for analysis of rifampicin in capsules.