Interactions of serum albumins with antitumor agent benzo [a] phenazine-a spectroscopic study

► Benzo [a] phenazine (BAP) specifically bounds with tryptophan present in HSA and BSA. ► Ground state of serum albumin quenches the excited BAP at 365 nm. ► Lifetime of serum albumins decreases in the presence of BAP. ► Photo-induced electron transfer from HSA and BSA to BAP takes place.