کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5403725 | 1392765 | 2007 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Interaction of the flavonoid hesperidin with bovine serum albumin: A fluorescence quenching study
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Interaction of the flavonoid hesperidin with bovine serum albumin: A fluorescence quenching study Interaction of the flavonoid hesperidin with bovine serum albumin: A fluorescence quenching study](/preview/png/5403725.png)
چکیده انگلیسی
The interaction between the flavonoid hesperidin and bovine serum albumin (BSA) was investigated by fluorescence and UV/Vis absorption spectroscopy. The results revealed that hesperidin caused the fluorescence quenching of BSA through a static quenching procedure. The hydrophobic and electrostatic interactions play a major role in stabilizing the complex. The binding site number n, and apparent binding constant KA, corresponding thermodynamic parameters ÎGo, ÎHo, ÎSo at different temperatures were calculated. The distance r between donor (BSA) and acceptor (hesperidin) was obtained according to fluorescence resonance energy transfer. The effect of Cu2+, Zn2+, Ni2+, Co2+, and Mn2+ on the binding constants between hesperidin and BSA were studied. The effect of hesperidin on the conformation of BSA was analyzed using synchronous fluorescence spectroscopy and UV/Vis absorption spectroscopy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Luminescence - Volume 126, Issue 1, September 2007, Pages 211-218
Journal: Journal of Luminescence - Volume 126, Issue 1, September 2007, Pages 211-218
نویسندگان
Yan-Qing Wang, Hong-Mei Zhang, Gen-Cheng Zhang, Wei-Hua Tao, Shu-He Tang,