کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5411650 1506579 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of phosphate group in switching off electron transfer in different media
ترجمه فارسی عنوان
اثر گروه فسفات در تعویض الکترون انتقال در رسانه های مختلف
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
چکیده انگلیسی
We have studied the interactions of individual nucleoside 5′-monophosphates of all the five nucleic acid bases, adenosine 5′-monophosphate (AMP), guanosine 5′-monophosphate (GMP), thymidine 5′-monophosphate (TMP), cytidine 5′-monophosphate (CMP) and uridine 5′-monophosphate (UMP) with two quinones, 9,10-anthraquinone (AQ) and 2-methyl 1,4-naphthoquinone (MQ) commonly known as menadione using laser flash photolysis in two different types of media. Although electron transfer (ET) in excited state is a well-known phenomenon in DNA with quinones, this work reveals a total failure of ET with these isolated 5′-monophosphate molecules in a homogeneous medium (acetonitrile/water), except GMP. Similar experiments in SDS micelles have been repeated but here even GMP failed to transfer electrons. We have attributed the failure of ET in homogeneous medium to a semi-circular conformation adopted by the 5′-monophosphates, which is assumed to pull back the electrons from the electron donor center, the nitrogenous base. In SDS micelles a rapid spin exchange within an abnormally short inter-radical distance has been considered to prevent ET.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Liquids - Volume 191, March 2014, Pages 92-99
نویسندگان
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