Arterial input function in perfusion MRI: A comprehensive review

- The arterial input function (AIF) is central to perfusion quantification.
- The AIF describes the contrast agent input to the tissue of interest.
- This review article covers the key issues related to the AIF in perfusion MRI.
- The issues of how and where to measure the AIF are discussed in detail.
- The effects that AIF errors have in perfusion quantification are also covered.