کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5435246 1509149 2017 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Novel impedimetric dopamine biosensor based on boronic acid functional polythiophene modified electrodes
ترجمه فارسی عنوان
بوسنسور دوپامین مؤثر بر اساس الکترودهای اصلاح شده پلیتیفن کاربردی اسید بورونی
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
چکیده انگلیسی


- Boronic acid functional polythiophene coated electrode was prepared for biosensor applications.
- The biosensor seems to be fast to respond and sensitive.
- Biosensors acquired good reproducibility, stability, selectivity and very low interference.

In this study we report a new, simple and first impedimetric biosensor based on 3-Thienyl boronic acid for dopamine detection. Biosensor electrode preparation is 1 min long by simple electro-polymerization of 3-Thienyl boronic acid and copolymer Thiophene P(TBA0.50Th0.50). Strong interaction between dopamine and thin layer of boronic acid has provided bio-sensing electrode high selectivity and stability, linear range of 7.8 to 125 μM, and detection limit of 0.3 μM. Characterization and optimization studies were conducted using electrochemical impedance spectroscopy (EIS) and cyclic voltammogram (CV). In order to test reliability of proposed biosensor real sample application study has been conducted using non-diluted human urine and it has been found that biosensor selectivity and recovery is excellent. As well P(TBA0.50Th0.50) based electrode and dopamine interaction has been proven by single frequency impedance measurements. Biosensors acquired good reproducibility, stability, selectivity and very low interference.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 72, 1 March 2017, Pages 641-649
نویسندگان
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