کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5462000 | 1398804 | 2016 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
An original route to target delivery via core-shell modification of SPIONs
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
فلزات و آلیاژها
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A adaptable method for grafting of amino group with polyethylene glycol (PEG) onto the surface of Superparamagnetic iron oxide nanoparticles (SPIONs) has been build up in order to develop magnetic core shell with enhanced properties (magnetic, colloidal stability, physico-chemical). In a straightforward and reproducible method new core shell SPIONs were developed based on diazonium salt chemistry highly and their application highly depends on monodispersity, size, and aqueous stability. The hydrodynamic size and zeta potential was studied as function of ionic strength. The surface morphology and average size distribution of magnetite nanoparticles was determined using transmission electron microscopy and diffraction pattern. The saturation magnetization was also achieved. With flexible surface chemistry, these surface modified SPIONs with amino groups could facilitate their use in biomedicine application by conjugating biomolecules improving the cellular targeting.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Today: Proceedings - Volume 3, Issue 8, 2016, Pages 2652-2661
Journal: Materials Today: Proceedings - Volume 3, Issue 8, 2016, Pages 2652-2661
نویسندگان
Manoj Singh, Alexander Savchenko, Igor Shetinin, Alexander Majouga,