Groove fibers based porous scaffold for cartilage tissue engineering application

A porous scaffold was prepared by gelatin groove fibers for cartilage tissue engineering. The morphology of groove fibers and porous scaffolds were observed by scanning electron microscopy (SEM). The water absorption property of scaffolds was tested which demonstrated values as high as 1187%. The compressive mechanical property of scaffolds was also evaluated. In wet state, this scaffold exhibited elastic behaviour, and could bear 100 cycles compressive fatigue test. Moreover, this scaffold could promote rat chondrocyte and bone marrow mesenchymal stem cells (BMSC) proliferation. The findings indicate that such scaffold could be valuable candidates for cartilage tissue engineering.