کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
54848 47028 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nano-organocatalysts synthesis: Boc vs Fmoc protection
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی کاتالیزور
پیش نمایش صفحه اول مقاله
Nano-organocatalysts synthesis: Boc vs Fmoc protection
چکیده انگلیسی

We report the elaboration of new l-Proline functionalized superparamagnetic iron oxide nanoparticles that can act as a new enantioselective organocatalyst. Boc-l-Proline and Fmoc-l-Proline are grafted using two different methodologies on a nanoplateform constituted of 10 nm maghemite (γ-Fe2O3) nanoparticle stabilized by bidendate coating agent Alendronate. We show that coupling is far more efficient using microwave assisted methodology and that only Fmoc deprotection is compatible with our nanoplatform. Moreover the fluorenyl group is used for indirect quantification of grafted Proline onto nanoparticles.

Figure optionsDownload high-quality image (85 K)Download as PowerPoint slideHighlights
► Elaboration of l-Proline functionalized iron oxide nanoparticles.
► Comparison of Boc and Fmoc strategies for the obtaining of the nano-organocatalyst.
► Complete characterization of the nano-organocatalyst.
► Uses of fluorenyl deprotection for the indirect quantification of grafted Proline.
► Enhancement of Proline grafting by using microwave assisted conditions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Catalysis Today - Volume 208, 1 June 2013, Pages 90–96
نویسندگان
, , ,