کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5485734 | 1399438 | 2017 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Acoustic Impedance Analysis with High-Frequency Ultrasound for Identification of Fatty Acid Species in the Liver
ترجمه فارسی عنوان
آنالیز امپدانس آکوستیک با سونوگرافی با فرکانس بالا برای شناسایی گونه های اسید چرب در کبد
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کلمات کلیدی
امپدانس آکوستیک، میکروسکوپ صوتی اسکن کردن، استاتو هپاتیت غیر الکلی، اسید چرب آزاد، کبد، قطره لیپید،
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
چکیده انگلیسی
Acoustic properties of free fatty acids present in the liver were studied as a possible basis for non-invasive ultrasonic diagnosis of non-alcoholic steatohepatitis. Acoustic impedance was measured for the following types of tissue samples: Four pathologic types of mouse liver, five kinds of FFAs in solvent and five kinds of FFAs in cultured Huh-7 cells. A transducer with an 80-MHz center frequency was incorporated into a scanning acoustic microscopy system. Acoustic impedance was calculated from the amplitude of the signal reflected from the specimen surface. The Kruskal-Wallis test revealed statistically significant differences (p < 0.01) in acoustic impedance not only among pathologic types, but also among the FFAs in solvent and in cultured Huh-7 cells. These results suggest that each of the FFAs, especially palmitate, oleate and palmitoleate acid, can be distinguished from each other, regardless of whether they were in solution or absorbed by cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 43, Issue 3, March 2017, Pages 700-711
Journal: Ultrasound in Medicine & Biology - Volume 43, Issue 3, March 2017, Pages 700-711
نویسندگان
Kazuyo Ito, Kenji Yoshida, Hitoshi Maruyama, Jonathan Mamou, Tadashi Yamaguchi,