کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5498342 1533363 2017 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Design of a new tracking device for on-line beam range monitor in carbon therapy
ترجمه فارسی عنوان
طراحی یک دستگاه ردیابی جدید برای نظارت بر روی خط پرتو در درمان کربن
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم تشعشع
چکیده انگلیسی
Charged particle therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbon ions. A critical issue is the monitoring of the beam range so to check the correct dose deposition to the tumor and surrounding tissues. The design of a new tracking device for beam range real-time monitoring in pencil beam carbon ion therapy is presented. The proposed device tracks secondary charged particles produced by beam interactions in the patient tissue and exploits the correlation of the charged particle emission profile with the spatial dose deposition and the Bragg peak position. The detector, currently under construction, uses the information provided by 12 layers of scintillating fibers followed by a plastic scintillator and a pixelated Lutetium Fine Silicate (LFS) crystal calorimeter. An algorithm to account and correct for emission profile distortion due to charged secondaries absorption inside the patient tissue is also proposed. Finally detector reconstruction efficiency for charged particle emission profile is evaluated using a Monte Carlo simulation considering a quasi-realistic case of a non-homogenous phantom.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physica Medica - Volume 34, February 2017, Pages 18-27
نویسندگان
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