کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5503743 1535595 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrochemical sensor for the detection of multiple reactive oxygen and nitrogen species from ageing central nervous system homogenates
ترجمه فارسی عنوان
سنسور الکتروشیمیایی برای شناسایی اکسیژن واکنش پذیر و انواع نیتروژن از سیستم های همگن سیستم های عصبی مرکزی پیری
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
چکیده انگلیسی
Reactive oxygen and nitrogen species (ROS/RNS) have been widely implicated in the ageing process and various approaches exist for monitoring these species in biological tissues. These approaches at present are limited to monitoring either a single pro-oxidant species or total pro-oxidant levels and therefore provide limited insight into the range of pro-oxidant species and their relative proportions in the ageing process. We have utilised a sensor that allows us to simultaneously monitor hydrogen peroxide, peroxynitrite, nitric oxide and nitrite. Using CNS homogenates from the pond snail, Lymnaea, we were able to show that levels of these ROS/RNS increased between young and old CNS homogenates and were different in various aged CNS regions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mechanisms of Ageing and Development - Volume 160, December 2016, Pages 28-31
نویسندگان
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