کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5553318 1557958 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Colon cancer targeting using conjugates biomaterial 5-flurouracil
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Colon cancer targeting using conjugates biomaterial 5-flurouracil
چکیده انگلیسی
There has been several research works on the development of an oral delivery system to deliver cytotoxic and chemo preventive agents directly at the targeted site of action with reduced unwanted side effects. The efficacy of the site-specific delivery system of a drug to colon has been proven to increase the drugs concentration at the target site, and thus requires a reduced dose of the drug with minimized side effects. This review includes discussion of the delivery systems of 5-FU using biodegradable materials and some significant outcomes in the pre-clinical development of 5-fluorouracil carriers for the colon cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Pharmacotherapy - Volume 84, December 2016, Pages 780-788
نویسندگان
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