کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5558863 1561225 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Platelet oxidative stress as a novel target of cardiovascular risk in frail older people
ترجمه فارسی عنوان
استرس اکسیداتیو پلاکت به عنوان یک هدف جدید در معرض خطر قلبی عروقی در افراد مسن ضعیف
کلمات کلیدی
پلاکت، بی خوابی، بیماری های قلبی عروقی، استرس اکسیداتیو،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

The average lifespan of humans and the percentage of people entering the 65 and older age group are growing rapidly. Within this age group, cardiovascular diseases (CVD) increase steeply and are the most common cause of death. During aging, experimental and clinical studies support the pivotal role played by reactive oxidant species in the mechanism of platelet activation. Frailty has been implicated as a causative and prognostic factor in patients with CVD. Oxidative stress is increased in frail older people, and may lead to accelerated aging and higher incidence of oxidative diseases such as CVD. The present article aims to highlight the relative contribution of platelet oxidative stress as a key target of frailty in elderly people with CVD.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vascular Pharmacology - Volumes 93–95, August 2017, Pages 14-19
نویسندگان
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