کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5560503 | 1561875 | 2017 | 7 صفحه PDF | دانلود رایگان |
In this study, the relationships between high water arsenic exposure and cognitive impairment were investigated. A total of 483 residents aged 40 or older were randomly recruited and were divided into four groups according to the concentrations of arsenic in their water. Consumption levels (Ìx¯ ± sd) of drinking water arsenic for normal, mild, moderate, and high exposure groups were 4 ± 2 μg/L, 25 ± 11 μg/L, 73 ± 15 μg/L, and 183 ± 88 μg/L, respectively. The average scores (Ìx¯ ± sd) of the Chinese version Mini-Mental State Examination (MMSE) for females in each group were 21.49 ± 3.14, 19.04 ± 5.87, 16.18 ± 8.14, and 15.82 ± 7.78, and the average scores (Ìx¯ ± sd) for males were 24.50 ± 3.97, 23.16 ± 4.45, 21.00 ± 6.57, and 18.92 ± 7.99, respectively. Significant differences among the average scores of MMSE for males or females in the four groups were found (p < 0.05). The prevalence of cognitive impairment for females in each group was 10.86%, 29.63%, 53.48%, and 55.29%, and the prevalence of cognitive impairment for males was 10.71%, 12.00%, 35.71%, and 50.89%, respectively. Significant differences between all groups were observed (p < 0.05). In the multivariable regress model, high water was closely associated with the MMSE score (Standardized Coefficient = â0.021) and cognitive impairment (arsenic Ë100âμg/L PR4/1 = 4.01). The findings of our research suggested a significant positive relationship between arsenic exposure from drinking water and cognitive impairment.
Journal: International Journal of Hygiene and Environmental Health - Volume 220, Issue 2, Part B, April 2017, Pages 424-430