کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5561673 | 1562152 | 2017 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A review of reproductive and developmental toxicity of silver nanoparticles in laboratory animals
ترجمه فارسی عنوان
بررسی سمیت تولید مثل و رشد نانوذرات نقره در حیوانات آزمایشگاهی
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
نانوذرات نقره، نانومواد، سمیت تولید مثل، سمیت اسپرم / بیضه، سمیت رشدی، عصبی رشدی، انتقال پلاستیکی، مانع خون بیضه،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
We summarized significant effects reported in the literature on the reproductive and developmental toxicity of silver nanoparticles (AgNPs) in laboratory animals. AgNPs showed testicular/sperm toxicity in males and ovarian and embryonic toxicity in females. Maternal injection of AgNPs delayed physical development and impaired cognitive behavior in offspring. Ag was accumulated in the testes after administration of AgNPs. AgNPs were identified in the visceral yolk sac after administration during early gestation in mice. Radiolabeled AgNPs were detected in placenta, breast milk, and pre- and postnatal offspring after injection during late gestation in rats. Ag in the ionic form, and possibly also particles, was suggested to be bioavailable. Although this review provides initial information on the potential reproductive and developmental toxicity of AgNPs, data is still very limited. Further studies using state-of-the-art methodologies and the relevant routes and doses for human exposure are required.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive Toxicology - Volume 67, January 2017, Pages 149-164
Journal: Reproductive Toxicology - Volume 67, January 2017, Pages 149-164
نویسندگان
Makoto Ema, Hirokazu Okuda, Masashi Gamo, Kazumasa Honda,