کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5566287 | 1563450 | 2016 | 4 صفحه PDF | دانلود رایگان |
BackgroundChlorhexidine-silver sulfadiazine (CHSS)-impregnated catheters have been found to decrease the risk of catheter-related bloodstream infection (CRBSI) and central venous catheter (CVC)-related costs. However, there are no published data about cost-effectiveness of the use of CHSS-impregnated catheters in subclavian venous access without the presence of tracheostomy (thus, with a very low risk of CRBSI). That was the objective of this study.MethodsThis was a retrospective study of patients admitted to a mixed intensive care unit who underwent placement of subclavian venous catheters without the presence of tracheostomy.ResultsPatients with standard catheters (nâ=â747) showed a higher CRBSI incidence density (0.95 vs 0/1,000 catheter-days; Pâ=â.02) and higher CVC-related cost per day ($3.78â±â$7.43 vs $3.31â±â$2.72; Pâ<â.001) than patients with a CHSS-impregnated catheter (nâ=â879). Exact logistic regression analysis showed that catheter duration (Pâ=â.02) and the type of catheter used (Pâ=â.01) were associated with the risk of CRBSI. Kaplan-Meier method showed that CHSS-impregnated catheters were associated with more prolonged CRBSI-free time than standard catheters (log-rankâ=â9.76; Pâ=â.002). Poisson regression analysis showed that CHSS-impregnated catheters were associated with a lower central venous catheter-related cost per day than standard catheters (odds ratio,â0.87; 95% confidence interval, 0.001-0.903; Pâ<â.001).ConclusionsThe use of CHSS-impregnated catheters is an effective and efficient measure for the prevention of CRBSI even at subclavian venous access sites without the presence of tracheostomy.
Journal: American Journal of Infection Control - Volume 44, Issue 12, 1 December 2016, Pages 1526-1529