کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5571808 | 1403836 | 2016 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Narkolepsie
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
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چکیده انگلیسی
Narcolepsy is a rare sleep-wake disorder. The main symptoms (cataplexy and excessive daytime sleepiness) are the result of a disorder of stage transition of wake, NREM and REM sleep. Narcolepsy therefore is considered to be a model disease for many other sleep-wake disorders. The symptoms are multi-facetted and display different phenotypes in children and youngsters as in adults, which cause difficulties in establishing the correct diagnosis. The psychosocial consequences differ according to the degree of the disorder and frequently cause incapacity to work or early retirement if the diagnosis is not established early. Unfortunately, latency to diagnosis is still very long and presently lasts up to 10 years in Europe. The reason for this long latency is the latency between the two main symptoms, excessive daytime sleepiness and cataplexy, or the very discrete presentation of symptoms, which can only be revealed by carefully taking medical history. Early diagnosis of narcolepsy is a hallmark to avoid the costly psychosocial consequences and the impairment of quality of life of patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Das Neurophysiologie-Labor - Volume 38, Issue 3, September 2016, Pages 127-138
Journal: Das Neurophysiologie-Labor - Volume 38, Issue 3, September 2016, Pages 127-138
نویسندگان
Geert Mayer,