کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5587498 1568820 2016 31 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A meta-analytic review of the correlation between peripheral oxytocin and cortisol concentrations
ترجمه فارسی عنوان
بررسی متاآنالیز از همبستگی بین اکسیتوسین محیطی و غلظت کورتیزول
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی
The stress dampening effects of exogenous oxytocin in humans have been well documented. However, the relation between endogenous oxytocin and cortisol is poorly understood. We conducted a meta-analysis on the correlation between oxytocin and cortisol levels measured at baseline (k = 24, N = 739). The effect size for the baseline correlation statistic was small (Pearson r = 0.163, p = 0.008), with high heterogeneity (I2 = 67.88%). Moderation analysis revealed that studies where participants anticipated an experimental manipulation evidenced a greater positive correlation compared to those that did not (Pearson r = 0.318, p = 0.006). A supplementary analysis including additional studies indicated that oxytocin levels in unextracted samples were 60 times higher when using this questionable practice. The findings suggest that the interplay between oxytocin and cortisol is dynamic and sensitive to the anticipation of stress or novelty. Furthermore, extraction of oxytocin appears to be an essential methodological practice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Frontiers in Neuroendocrinology - Volume 43, October 2016, Pages 19-27
نویسندگان
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