کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5621741 | 1406153 | 2016 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Short communicationThe association between poor sleep quality and global cortical atrophy is related to age. Results from the Atahualpa Project Short communicationThe association between poor sleep quality and global cortical atrophy is related to age. Results from the Atahualpa Project](/preview/png/5621741.png)
Community-dwellers aged â¥60 years enrolled in the Atahualpa Project underwent brain MRI and were interviewed with the Pittsburgh Sleep Quality Index. Of 290 participants, 94 (32%) had poor sleep quality and 143 (49%) had global cortical atrophy (GCA). In a logistic regression model (adjusted for demographics, cardiovascular risk factor, severe edentulism, symptoms of depression, the MoCA score, and neuroimaging signatures of cerebrovascular damage), poor sleep quality was associated with GCA (p=0.004). A multivariate probability model showed that the probability of moderate-to-severe GCA significantly increased in individuals with poor sleep quality aged â¥67 years. This study provides evidence for an association between poor sleep quality and GCA in older adults and the important interaction of age in this association.
Journal: Sleep Science - Volume 9, Issue 3, JulyâSeptember 2016, Pages 147-150