کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5624717 1406258 2007 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Review articleGenetics and dementia: Risk factors, diagnosis, and management
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Review articleGenetics and dementia: Risk factors, diagnosis, and management
چکیده انگلیسی

New developments in molecular genetics have improved our understanding on a number of neurodegenerative dementias considerably, especially Alzheimer's disease and frontotemporal dementia. However, this explosion of information can be overwhelming to clinicians, making it difficult to integrate into regular clinical practice. In this article, we briefly reviewed our current understanding regarding causative genetic mutations and genetic risk factors on the major forms of dementia, which provided the background information for discussion in the Third Canadian Consensus Conference on the Diagnosis and Treatment of Dementia. The principles of genetic counselling were applied. Guidelines and recommendations on the application of genetics in the assessment, diagnosis, and management of patients and families with dementia were summarized.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Alzheimer's & Dementia - Volume 3, Issue 4, October 2007, Pages 418-427
نویسندگان
, ,