کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5633820 1406598 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Results of Conservative Follow-up or Surgical Treatment of Moyamoya Patients Who Present without Hemorrhage, Transient Ischemic Attack, or Stroke
ترجمه فارسی عنوان
نتایج مراقبتهای محافظهکارانه یا جراحی بیماران مومیایی که بدون خونریزی، حمله ایسکمیک گذرا یا سکته مغزی هستند
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
چکیده انگلیسی

ObjectiveThe epidemiology of asymptomatic moyamoya disease (MMD) is still unclear, and the best management remains controversial. The aim of this study is to evaluate the prognosis of these patients with different management, conservative follow-up, or surgical treatment.MethodsThis prospective cohort study screened a series of 696 consecutive MMD patients from 2009-2015. Patients with any episodes of hemorrhage and ischemic stroke or TIA were excluded. Finally, 61 patients who were followed up for at least 12 months were included, with 52 patients who underwent surgical treatment and 9 patients who underwent conservative follow-up. Patients were divided into 2 groups: surgical and conservative. Advert events including newly hemorrhage and ischemic stroke and death were compared between the groups. Relationships between disease progression and collaterals and cerebral blood flow were analyzed separately.ResultsThe mean follow-up period was 56.32 months (range, 11.3-112.62 months). During the follow-up period, 3 patients had symptomatic progression in the conservative group, 1 suffered a hemorrhage, and 2 had TIAs. Among the patients in the surgical group, 6 of them experienced TIAs. Kaplan-Meier analysis showed that patients receiving surgeries had a longer symptom-free time compared with patients in the conservative group (P = 0.015). Decreased cerebral blood flow had no influence on disease progression in patients in both groups. Existence of extracranial to intracranial collaterals showed a better outcome for patients in the surgical group but not the conservative group.ConclusionsSurgical treatment may be a better choice for patients with asymptomatic MMD. And patients with better collateral circulations, especially extracranial to intracranial collateral arteries, may have a better prognosis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: World Neurosurgery - Volume 108, December 2017, Pages 683-689
نویسندگان
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