کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5657892 | 1407414 | 2017 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Non-alcoholic fatty liver disease and flavonoids: Current perspectives
ترجمه فارسی عنوان
بیماری کبد چرب غیر الکلی و فلاونوئیدها: دیدگاه های جاری
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کلمات کلیدی
ABCA1NAFLDATP-binding cassette sub-family A member 1SREBP2VLDLAMPKGPXEGCGGSHHDLNon-alcoholic steatohepatitis - استئاتوهپاتیت غیرالکلیepigallocatechin gallate - اپی گالوستاچین گالاتnon-alcoholic fatty liver diseases - بیماری های کبدی چربی غیر الکلیSOD - سدSuperoxide dismutase - سوکسوکس دیسموتازhigh density lipoproteins - لیپوپروتئینهای چگالی بالاvery low density lipoproteins - لیپوپروتئینهای چگالی بسیار کمNash - نوشGlutathione - گلوتاتیونglutathione peroxidase - گلوتاتیون پراکسیداز
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
چکیده انگلیسی
Non-alcoholic fatty liver disease (NAFLD) is an accumulation of fat in the liver despite a low level of alcohol intake, with signs of hepatomegaly. Although in the past, NAFLD was predominantly viewed as an aspect of metabolic syndrome, it is now considered that it should be classified as an independent condition similar to obesity, diabetes, and hypertension. Therefore, new treatment strategies, not based on correcting insulin resistance, are needed for NAFLD. This work analyzes methods of prevention, therapeutic approaches, and mechanisms involved in NAFLD, focusing on the use of flavonoids (epigallocatechin-3-gallate, resveratrol, anthocyanins, and isoflavones) with high antioxidant capacity. In addition, the mechanisms of cholesterol accumulation in the liver are identified as potential avenues for entirely new approaches to NAFLD treatment, contrasting the well-known relation between neutral fat and NAFLD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinics and Research in Hepatology and Gastroenterology - Volume 41, Issue 1, February 2017, Pages 17-24
Journal: Clinics and Research in Hepatology and Gastroenterology - Volume 41, Issue 1, February 2017, Pages 17-24
نویسندگان
Jung Hee Shin, Ji Hye Jung,