کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5658309 | 1407431 | 2017 | 57 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Diet as a Trigger or Therapy for Inflammatory Bowel Diseases
ترجمه فارسی عنوان
رژیم غذایی به عنوان یک عامل یا درمان برای بیماری های التهابی روده
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
TNFFGSH2SGPR43SRBSCDFODMAPMCTSCFAIBDHFDPolyunsaturated fatty acids - اسید چرب اشباع نشدهPUFA - اسید چرب چند غیراشباعshort-chain fatty acid - اسید چرب کوتاه مدتShort-chain fatty acids - اسیدهای چرب کوتاه مدتinterleukin - اینترلوکینSulfate-reducing bacteria - باکتری های کاهش سولفاتCrohn’s disease - بیماری کرونInflammatory bowel disease - بیماریهای التهابی رودهMedium-chain triglyceride - تری گلیسرید متوسط زنجیره ایExclusive enteral nutrition - تغذیه انتروال منحصر به فردPEN - خودکارDiet - رژیم غذاییhigh-fat diet - رژیم غذایی با چربی بالاHydrogen sulfide - سولفید هیدروژنtumor necrosis factor - فاکتور نکروز تومورMicrobiome - میکروبیومUlcerative colitis - کولیت اولسراتیوEEN - یکی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
چکیده انگلیسی
The most common question asked by patients with inflammatory bowel disease (IBD) is, “Doctor, what should I eat?” Findings from epidemiology studies have indicated that diets high in animal fat and low in fruits and vegetables are the most common pattern associated with an increased risk of IBD. Low levels of vitamin D also appear to be a risk factor for IBD. In murine models, diets high in fat, especially saturated animal fats, also increase inflammation, whereas supplementation with omega 3 long-chain fatty acids protect against intestinal inflammation. Unfortunately, omega 3 supplements have not been shown to decrease the risk of relapse in patients with Crohn's disease. Dietary intervention studies have shown that enteral therapy, with defined formula diets, helps children with Crohn's disease and reduces inflammation and dysbiosis. Although fiber supplements have not been shown definitively to benefit patients with IBD, soluble fiber is the best way to generate short-chain fatty acids such as butyrate, which has anti-inflammatory effects. Addition of vitamin D and curcumin has been shown to increase the efficacy of IBD therapy. There is compelling evidence from animal models that emulsifiers in processed foods increase risk for IBD. We discuss current knowledge about popular diets, including the specific carbohydrate diet and diet low in fermentable oligo-, di-, and monosaccharides and polyols. We present findings from clinical and basic science studies to help gastroenterologists navigate diet as it relates to the management of IBD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gastroenterology - Volume 152, Issue 2, January 2017, Pages 398-414.e6
Journal: Gastroenterology - Volume 152, Issue 2, January 2017, Pages 398-414.e6
نویسندگان
James D. Lewis, Maria T. Abreu,