کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5664645 1407716 2017 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Extra corporeal photochemotherapy in steroid refractory graft versus host disease: A review of guidelines and recommendations
ترجمه فارسی عنوان
فتوتراپی فوق العاده جراحی مقاوم در برابر استروئید در برابر بیماری های میزبان: بررسی دستورالعمل ها و توصیه ها
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
چکیده انگلیسی

Regardless of remarkable progresses in prevention and treatment approaches, graft versus host disease (GVHD) remains a major impediment for successful allogeneic hematopoietic stem cells transplantation (HSCT) and leads to morbidity and mortality in transplanted patients. Corticosteroids are the standard therapy for GVHD; however, a great number of patients will not respond sufficiently and others will be significantly affected by adverse effects of steroids. Extracorporeal photochemotherapy (ECP), as one of the numerous second line therapies, through modulation of immune cells may improves GVHD affected organ function in steroid-refractory forms. Considering to widespread utilization of ECP as a therapeutic strategy, we performed review on current literature of ECP, regarding the treatment strategies, monitoring protocols and technical aspects in chronic and acute GVHD.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transfusion and Apheresis Science - Volume 56, Issue 3, June 2017, Pages 376-384
نویسندگان
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