کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5671875 | 1408072 | 2016 | 27 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
First next-generation sequencing full-genome characterization of a hepatitis C virus genotype 7 divergent subtype
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: First next-generation sequencing full-genome characterization of a hepatitis C virus genotype 7 divergent subtype First next-generation sequencing full-genome characterization of a hepatitis C virus genotype 7 divergent subtype](/preview/png/5671875.png)
چکیده انگلیسی
We report the near-full-length genome sequence of a hepatitis C virus (HCV) isolate from a man originating from Democratic Republic of Congo, the genotype of which could not be determined by the routinely used sequencing technique. The near-complete genome sequence of this variant BAK1 was obtained by the association of two next-generation sequencing technologies. Evolutionary analysis indicates that this isolate, BAK1, could be the first reported strain belonging to a new HCV-7b subtype. This new subtype has been incorrectly identified as genotype 2 by the Versant HCV Genotype 2.0 assay (LiPA). The requirement of three independent isolates has been filled, and a new subtype can be assigned. More examples of HCV-7 are required to better understand its origin, its pathogenicity and its relationship with genotype 2.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Microbiology and Infection - Volume 22, Issue 11, November 2016, Pages 947.e1-947.e8
Journal: Clinical Microbiology and Infection - Volume 22, Issue 11, November 2016, Pages 947.e1-947.e8
نویسندگان
M. Salmona, A. Caporossi, P. Simmonds, M.-A. Thélu, K. Fusillier, S. Mercier-Delarue, N. De Castro, J. LeGoff, M.-L. Chaix, O. François, F. Simon, P. Morand, S. Larrat, S. Maylin,