کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5672155 | 1593175 | 2017 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The emerging principles for acne biogenesis: A dermatological problem of puberty
ترجمه فارسی عنوان
اصول در حال ظهور بیوگرافی آکنه: یک مشکل پوستی بلوغ
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
چکیده انگلیسی
Acne is the most common conditional skin infection in late adolescence. It has long played the part of 'Black Spot' against Natural Beauty, characterized by non-inflammatory pilosebaceous lesions of open or closed comedons, and inflammatory lesions of papules, pustules and nodules. It is typically affected the face, neck, and upper trunk area, where sebaceous follicles is densest in population, however prevalence is about 90% in teenagers. Recent advances have been made in this area with the discovery of Propionibacterium acnes interaction with Toll-Like Receptors (TLRs) and free fatty acid that initiates linoleic deficiency, also the role of linoleic acid and PPARs (peroxisome proliferators-activated receptors) in inflammation. However multi-drug resistant of bacteria by biofilm formation is also a matter of concern, that render the course of treatment ineffective. With all relevant literature database search upto recent this review focuses on pathogenesis of acne and mechanisms involved in the development of inflammation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Human Microbiome Journal - Volume 4, June 2017, Pages 7-13
Journal: Human Microbiome Journal - Volume 4, June 2017, Pages 7-13
نویسندگان
Afifa Qidwai, Manisha Pandey, Sarvesh Pathak, Rajesh Kumar, Anupam Dikshit,