کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5672242 | 1593184 | 2017 | 4 صفحه PDF | دانلود رایگان |
- This is the first case of a group A streptococcal infection with pleural empyema & toxic shock syndrome in a healthy man.
- He developed epidermolysis at peripheral sites of the hand and foot as the typical manifestations.
- This isolate possessed emm1, sequence type 28, sic1.02, speA-speB-smeZ, and mef(A), respectively.
Group A Streptococcus (GAS, Streptococcus pyogenes) causes invasive infections including streptococcal toxic shock syndrome (STSS) and local infections. To our knowledge, this is the first report of a case of an invasive GAS infection with pneumonia and pleural empyema (PE) followed by STSS (disseminated intravascular coagulation [DIC] and acute renal insufficiency) in a healthy male adult. He received combined supportive therapies of PE drainage, anti-DIC agent, hemodialysis, and antimicrobials and eventually made a clinical recovery. GAS isolated from PE was found to have emm1/speA genes, suggestive of a pathogenic strain. Clinicians should be aware of the possibility of this disease entity (pneumonia, PE, and STSS) in healthy male adults as well as children and adult women.
Journal: IDCases - Volume 9, 2017, Pages 85-88