کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5673622 | 1593678 | 2017 | 18 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Study on the excision and integration mediated by class 1 integron in Streptococcus pneumoniae
ترجمه فارسی عنوان
بررسی برداشت و ادغام شده توسط انتگرال کلاس 1 در استرپتوکوک پنومونیه
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
چکیده انگلیسی
As a novel antibiotic resistance mobile element, integron was recognized as a primary source of antibiotic genes among Gram-positive organisms for its excision and integration of exogenous genes. In this study, Streptococcus pneumoniae was subjected to investigate the excision and integration of class 1 integron with eight different plasmids. As the results indicated, excision in both att site and gene cassettes were successfully observed, which was further confirmed by integration assays and PCR amplification. The observation of class 1 integron mediated excision and integration of various exogenous antibiotics resistance genes may raise the attention of integrons as novel antibiotic resistance determinant in Gram-positive bacteria, especially in Streptococcus.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microbial Pathogenesis - Volume 111, October 2017, Pages 446-449
Journal: Microbial Pathogenesis - Volume 111, October 2017, Pages 446-449
نویسندگان
Qun Lin, Pusheng Xu, Jiaowu Li, Jinhua Huang, Yin Chen, Shuhuan Deng,