کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5673853 | 1593680 | 2017 | 4 صفحه PDF | دانلود رایگان |
- RMF enhances the prophage-induction effect of mitomycin C.
- 50Â Hz rotating magnetic field alters the induction of Stx prophage.
- Effect of 50Â Hz RMF is strain specific.
Studies aimed at investigating factors and mechanism of induction of prophages, a major pathogenesis factor of Shiga toxin-producing Escherichia coli (STEC), are considered important to develop an effective treatment for STEC infections. In this study, we demonstrated the synergistic effect of the rotating magnetic field (RMF) of induction B = 34 mT and frequency Æ = 50 Hz at a constant temperature of 37 °C and mitomycin C (MMC), that resulted in a higher level of induction of stx-carrying lambdoid Stx prophages. This is a first report on the induction of lambdoid Stx prophages in response to the enhancing effect of popular inductor (mitomycin C) under the influence of RMF.
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Journal: Microbial Pathogenesis - Volume 109, August 2017, Pages 4-7