کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5674928 | 1594208 | 2017 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Immune activation in prolonged cART-suppressed HIV patients is comparable to that of healthy controls
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ویروس شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Immune activation in prolonged cART-suppressed HIV patients is comparable to that of healthy controls Immune activation in prolonged cART-suppressed HIV patients is comparable to that of healthy controls](/preview/png/5674928.png)
چکیده انگلیسی
We performed a comprehensive analysis including cellular, intracellular and plasma biomarkers to study the effect of cART on immune parameters in 5 groups of 10 HIV patients. All patients were without major co-morbidities and grouped based on cART duration (0, 1, 3, 5, and 10 years). We included 10 matched healthy controls for comparison. Our data show that after the first year of cART, no additional effect on the level of inflammatory markers is observed in HIV infected patients without major co morbidities. Residual immune activation status in well-treated HIV-infection is similar to levels observed in healthy controls.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Virology - Volume 509, September 2017, Pages 133-139
Journal: Virology - Volume 509, September 2017, Pages 133-139
نویسندگان
Lennert van den Dries, Mark A.A. Claassen, Zwier M.A. Groothuismink, Eric van Gorp, Andre Boonstra,