کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5738089 1615041 2017 22 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A structural motor network correlates with motor function and not impairment post stroke
ترجمه فارسی عنوان
یک شبکه موتور ساختاری با عملکرد حرکتی ارتباط دارد و نه پس از سکته مغزی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
چکیده انگلیسی
Combining structural and functional magnetic resonance imaging may provide insight into how residual motor networks contribute to motor outcomes post-stroke. The purpose of this study was to examine whether a structural motor network (SMN), generated with fMRI guided diffusion-based tractography, relates to motor function post-stroke. Twenty-seven individuals with mild to moderate upper limb impairment post stroke underwent diffusion magnetic resonance imaging. A bilateral motor network mask guided white matter tractography for each participant. Fractional anisotrophy (FA) was calculated for the SMN and corticospinal tracts (CST). The Wolf Motor Function Test (WMFT) rate and Fugl-Meyer Upper Limb (FM) tests characterized arm function and impairment respectively. The SMN and ipsilesional CST together explained approximately 35% of the variance in paretic arm function (WMFT-rate p = 0.006). This study demonstrates that a broader motor network, like the SMN, is functionally meaningful. Given that the motor network is widely distributed, the proposed SMN warrants further investigation as a potential adjunct biomarker to characterize recovery potential after stroke.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 658, 29 September 2017, Pages 155-160
نویسندگان
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