کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5760361 1623986 2017 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optimizing bicoid signal extraction
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
Optimizing bicoid signal extraction
چکیده انگلیسی
Signal extraction and analysis is of great importance, not only in fields such as economics and meteorology, but also in genetics and even biomedicine. There exists a range of parametric and nonparametric techniques which can perform signal extractions. However, the aim of this paper is to define a new approach for optimising signal extraction from bicoid gene expression profile. Having studied both parametric and nonparametric signal extraction techniques, we identified the lack of specific criteria enabling users to select the optimal signal extraction parameters. Exploiting the expression profile of bicoid gene, which is a maternal segmentation coordinate gene found in Drosophila melanogaster, we introduce a new approach for optimising the signal extraction using a nonparametric technique. The underlying criteria are based on the distribution of the residual, more specifically its skewness.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mathematical Biosciences - Volume 294, December 2017, Pages 46-56
نویسندگان
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