کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5775183 1413577 2017 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Analysis of a mathematical model for tumor growth with Gibbs-Thomson relation
ترجمه فارسی عنوان
تجزیه و تحلیل یک مدل ریاضی برای رشد تومور با رابطه گیبس-تامسون
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات آنالیز ریاضی
چکیده انگلیسی
In this paper we study a mathematical model for the growth of nonnecrotic solid tumor. The tumor is assumed to be radially symmetric and its radius R(t) is an unknown function of time t as tumor growth, and the model is in the form of a free boundary problem. The feature of the model is that a Gibbs-Thomson relation is taken into account, which results an interesting phenomenon that there exist two stationary solutions (depending on the model parameters). The global existence and uniqueness of solution are established. By denoting c the ratio of the diffusion time scale to the tumor doubling time scale, we prove that for sufficiently small c>0, the stationary solution with the larger radius is asymptotically stable, and the other smaller one is unstable.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Mathematical Analysis and Applications - Volume 450, Issue 1, 1 June 2017, Pages 532-543
نویسندگان
,