کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5802803 | 1555682 | 2014 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Assessing the speed of kill of hookworms, Ancylostoma caninum, by Advantage Multi® for Dogs using endoscopic methods Assessing the speed of kill of hookworms, Ancylostoma caninum, by Advantage Multi® for Dogs using endoscopic methods](/preview/png/5802803.png)
Endoscopic capsules and endoscopy were used to assess the speed of kill and the clearance of hookworms in dogs experimentally infected with Ancylostoma caninum. A total of four adult dogs were inoculated in two separate cohorts comprised of two 4-year-old females and two 7-year-old males. Dogs were treated topically with Advantage Multi® for Dogs 13 days (Cohort 1) or 16 days (Cohort 2) after infection. Endoscopic imaging of the small intestine was carried out both pre- and post-treatment. Examination of the first cohort revealed that the worms had been cleared and the hookworm-induced lacerations were markedly diminished within 48Â h of treatment. In the second cohort, endoscopic capsules were given the day of, the day after, and two days after treatment; within 24Â h of product administration, the worms had been removed with a concurrent reduction in observed lesions. Topical application of Advantage Multi® for Dogs rapidly removed worms from the small intestine of the dogs in this study as early as 24Â h post-treatment, with a marked reduction in the number of mucosal lesions seen.
Journal: Veterinary Parasitology - Volume 204, Issues 3â4, 29 August 2014, Pages 402-406