Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: Effects of fluoxetine and MK-801

► Chronic stress induces contrasted adaptive changes in different strains of mice. ► BDNF and VGLUT1 are markers for these adaptive changes. ► BDNF and VGLUT1 levels changes are not correlated to antidepressant effects. ► CUMS on C57BL/6 and BALB/c strains models atypical vs. melancholic depression.