Keywords: EB; embryoid body; ESC; embryonic stem cell; GAD67; glutamate decarboxylase 67â¯kDa isoform; GFAP; glial fibrillary acidic protein; MBP; myelin-basic protein; OLIG1/2; oligodendrocyte transcription factor 1/2; SOX2/10; SRY-box 2/10; S100β; S100 calcium
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Keywords: CSDS; chronic social defeat stress; CYT; cytosol; DAB; diaminobenzidine; Gln; glutamine; GLT-1; glutamate transporter-1; Glu; glutamate; HRP; horseradish peroxidase; MD; major depression; Mit; mitochondrion; NAc; nucleus accumbens; PAG; phosphate-activate
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptor; AP5; 2-amino-5-phosphonopentanoic acid; ATPA; (RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl) propanoic acid; AUC; area under the curve; CNS; central nervous system; C
Keywords: 5-HT; serotonin (5-hydroxytryptamine); A83-01; TGF-β kinase/activin receptor-like kinase inhibitor; ACTB; actin beta/beta-actin; ASCL1; achaete-scute homolog 1 (MASH1); ASOs; anti-sense oligonucleotides; Bcl-xL; b-cell lymphoma-extra large; BDNF; brain d
Keywords: C1m; rats subjected to 1Â month of compression; C1m-D14d; rats subjected to 1Â month of compression and then decompressed for 14Â days; C1w; rats subjected to 1Â week of epidural compression; C1w-D14d; rats subjected to 1Â week of compression and then dec
Keywords: BDNF; brain-derived neurotrophic factor; DA; dopamine; DAT; dopamine transporter; DL; dorsolateral; EAAC1; excitatory amino acid carrier 1; GFAP; glial fibrillary acidic protein; GLAST; glutamate aspartate transporter; GLT-1; glutamate transporter 1; IHC;
Keywords: Ischemia; Brain preconditioning; Neuroprotection; Functional food; Synaptogenesis; Neurogenesis; ALA; alpha-linolenic acid; ANSES; Agence Nationale pour la Sécurité et la Santé; BDNF; brain derived neurotrophic factor; CVD; cardiovascular diseases; DHA
Keywords: ATP1A2; sodium/potassium-transporting ATPase subunit alpha-2; CMS; chronic mild stress; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; GFAP; glial fibrillary acidic protein; HOMER1; homer protein homolog 1; iTRAQ; isobaric tags for relative a
Keywords: 5-HIAA; 5-hydroxyindolacetic acid; 5-HT; serotonin; 6-OHDA; 6-hydroxydopamine; AIMs; Abnormal involuntary movements; ARC; activity-regulated cytoskeletal-associated protein; DA; dopamine; DOPAC; 3,4-dihydroxyphenylacetic acid; EDTA; ethylenediaminetetraac
Keywords: CNS; central nervous system; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; ES cell; embryonic stem cell; NPC; neural progenitor cell; CA; cellular aggregate; N2M; N2 medium; CM; complete medium; SBM; the Nerve-Cell Culture
Keywords: VGluT1; VGluT2; Primary auditory cortex; Quantitative microscopy; Stereology; Postmortem human tissue;
Keywords: ALS; amyotrophic lateral sclerosis; ANOVA; analysis of variance; CGRP; calcitonin gene-related peptide; FL; full-length; GFAP; glial fibrillary acidic protein; GSK-3β; glycogen synthase kinase-3β; Iba1; ionized calcium-binding adaptor molecule 1; Li; li
5-HT1B receptor agonist CGS12066 presynaptically inhibits glutamate release in rat hippocampus
Keywords: CGS12066; 7-trifluoromethyl-4-(4-methyl-1-piperaziny)pyrrolo-[1,2-a]quinoxaline; 5-HT1B receptors; 5-hydroxytryptamine 1B receptors; 4-AP; 4-aminopyridine; GPCR; G protein-coupled receptor; AC; adenylate cyclase; PKA; protein kinase A; VGLUT1; vesicular t
Neuropeptide Y as a possible homeostatic element for changes in cortical excitability induced by repetitive transcranial magnetic stimulation
Keywords: Parvalbumin; Fast-spiking interneurons; Glutamatergic transmission; Homeostatic regulation of inhibition; Transcranial magnetic stimulation; ANOVA; analysis of variance; FSI; fast-spiking interneurons; iTBS; intermittent theta-burst stimulation; LTD; long
5-HT2A-mGlu2/3 receptor complex in rat spinal cord glutamatergic nerve endings: A 5-HT2A to mGlu2/3 signalling to amplify presynaptic mechanism of auto-control of glutamate exocytosis
Keywords: mGlu2/3 receptor; 5-HT2A receptor; Glutamate release; Spinal cord; GPCR crosstalk; Heterocomplex; mGlu2/3; metabotropic glutamate receptor type 2/3; 5-HT2A; serotonin type 2A; [3H]D-Asp; [3H]D-aspartate; CNS; central nervous system; EPSCs; excitatory post
Impaired glutamatergic projection from the motor cortex to the subthalamic nucleus in 6-hydroxydopamine-lesioned hemi-parkinsonian rats
Keywords: STN; subthalamic nucleus; PD; Parkinson's disease; HSV-GFP; herpes simplex virus-green fluorescent protein; HSV-1; herpes simplex virus type 1; VGluT1; vesicular glutamate transporter 1; M1; primary motor cortex; 6-OHDA; 6-hydroxydopamine; GPi; globus pal
Involvement of SNARE complex in the hippocampus and prefrontal cortex of offspring with depression induced by prenatal stress
Keywords: Prenatal stress; Depression; SNARE protein; vGluT1; ADHD; attention deficit hyperactivity disorder; CSPα; cysteine-string protein-α; EAAT; excitatory amino acid transporter; EPM; elevated plus maze; FST; forced swimming test; Munc-18; mammalian uncoordi
Modulation of P2X7 purinergic receptor activity by extracellular Zn2+ in cultured mouse hippocampal astroglia
Keywords: CNS; central nervous system; MDD; major depressive disorder; BzATP; 3â²-O-(4-Benzoyl) benzoyl ATP; BBG; Brilliant Blue G; OGB-1; OregonGreen Bapta-1; PI; propidium iodide; VGluT1; vesicularglutamate transporter 1; P2X7R; Hippocampus; Purinergic receptor;
Sculpting neurotransmission during synaptic development by 2D nanostructured interfaces
Keywords: AFM; atomic force microscopy; CT-B; Cholera Toxin subunit-B; DIV; days in vitro; DOPC; 1,2-Dioleoyl-sn-glycero-3-phosphocholine; MβCD; Methyl-β-Cyclodextrin; mPSCs; miniature post-synaptic currents; MWCNTs; multi-walled carbon nanotubes; PSCs; post-syna
A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability
Keywords: aCSF; artificial cerebrospinal fluid; CCI; chronic constriction injury; CGRP; calcitonin gene-related peptide; Cy3; indocarbocyanine; ERK; extracellular signal-regulated kinase; GFAP; glial fibrillary acidic protein; IB4; isolectin B4; Iba1; ionized calci
Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease
Keywords: α-Syn; alpha-Synuclein; h-α-Syn; transgenic human alpha-Synuclein; D1 receptor; dopamine receptor type 1; D2 receptor; dopamine receptor type 2; DA; dopamine; DAT; dopamine transporter; VMAT2; vesicular monoamine transporter 2; DOPAC; 3,4-dihydroxypheny
Pyridazine-derivatives Enhance Structural and Functional Plasticity of Tripartite Synapse Via Activation of Local Translation in Astrocytic Processes
Keywords: Ank2; ankyrin-2; AP-2; adaptor complex 2 subunit; APP; amyloid precursor protein; AUC; area under the curve; BDNF/NT-3; brain-derived neurotrophic factor and neurotrophin-3 receptor; CDS; coding sequence; CLTB; clathrin light-chain B; EAAT1/GLAST; excitat
Genetically encoded fluorescent indicators for live cell pH imaging
Keywords: FP; fluorescent protein; avGFP; green fluorescent protein from Aequorea victoria; FRET; Förster resonance energy transfer; wt; wild-type; ESPT; excited state proton transfer; pHi; intracellular pH; EGFP; enhanced GFP; ECFP; enhanced cyan fluorescent prot
The histology, physiology, neurochemistry and circuitry of the substantia gelatinosa Rolandi (lamina II) in mammalian spinal cord
Keywords: [Ca2+]i; intracellular Ca2+ concentration; 5-HT; serotonin; Ach; acetylcholine; AMP; adenosine monophosphate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptor; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin;
Short communicationSIRT2 inhibition reverses anhedonia in the VGLUT1+/â depression model
Keywords: BDNF; brain-derived neurotrophic factor; HDAC; histone deacetylase; PFC; prefrontal cortex; VGLUT1; vesicular glutamate transporter 1; Anhedonia; Imipramine; Histone acetylation; Sirtuin 2 (SIRT2); Prefrontal cortex (PFC); 33i; Major depression;
Altered synaptobrevin-II trafficking in neurons expressing a synaptophysin mutation associated with a severe neurodevelopmental disorder
Keywords: SV; synaptic vesicle; sybII; synaptobrevin II; CV; coefficient of variation; vGLUT1; vesicular glutamate transporter 1; SNARE; soluble N-ethylmaleimide sensitive factor attachment protein receptor; mOr2; mOrange2; Synaptic vesicle; Endocytosis; Neuron; Ne
Botulinum neurotoxin type A-cleaved SNAP25 is confined to primary motor neurons and localized on the plasma membrane following intramuscular toxin injection
Keywords: 2D; 2 dimensional; BoNT/A; botulinum neurotoxin type A; ChAT; choline acetyltransferase; CNS; central nervous system; CTB AF-488; cholera toxin B subunit Alexa Fluor 488 conjugate; DAS; digit abduction score; GAD; glutamic acid decarboxylase; GFAP; glial
Function and expression of a splicing variant of vesicular glutamate transporter 1
Keywords: DIDS; diisothiocyanatostilbene disulfonic acid; ÎÏ; membrane potential; VGAT; vesicular GABA transporter; VGLUT; vesicular glutamate transporter; VGLUT1v; vesicular glutamate transporter 1 variant; GCL; ganglion cell layer; IPL; inner plexiform layer; I
Distinctive features of Phox2b-expressing neurons in the rat reticular formation dorsal to the trigeminal motor nucleus
Keywords: AHP; afterhyperpolarization; amp; amplitude; AP; action potential; 4-AP; 4-aminopyridine; BAC; bacterial artificial chromosome; Ccell; cell capacitance; CCHS; congenital central hypoventilation syndrome; DAB; 3,3â²-diaminobenzidine tetrahydrochloride; DA
Changes in VGLUT1 and VGLUT2 expression in rat dorsal root ganglia and spinal cord following spared nerve injury
Keywords: Dorsal root ganglia; Neuropathic pain; Spinal cord; VGLUT1; VGLUT2
Early-onset motor impairment and increased accumulation of phosphorylated α-synuclein in the motor cortex of normal aging mice are ameliorated by coenzyme Q
Keywords: PD; Parkinson's disease; CoQ; coenzyme Q; Q; oxidized coenzyme Q; QH2; reduced coenzyme Q; OCR; oxygen consumption rate; α-syn; alpha-synuclein; VGluT1; vesicular glutamate transporter 1; SNc; substantia nigra pars compacta; LBs; Lewy bodies; TH; tyrosin
Colocalization of synapse marker proteins evaluated by STED-microscopy reveals patterns of neuronal synapse distribution in vitro
Keywords: GABA; γ-aminobutyric acid; Geph; gephyrin; PNNs; perineuronal nets; PSD95; postsynaptic density protein 95 kDa; STED; stimulated emission depletion; VGAT; vesicular γ-aminobutyric acid transporter; VGLUT1; vesicular glutamate transporter; Synapse quant
Immunostaining for Homer reveals the majority of excitatory synapses in laminae I-III of the mouse spinal dorsal horn
Keywords: CGRP; calcitonin gene-related peptide; DAB; diaminobenzidine; IB4; isolectin B4; LTMR; low-threshold mechanoreceptor; VGAT; vesicular GABA transporter; VGLUT1; vesicular glutamate transporter 1; VGLUT2; vesicular glutamate transporter 2; glutamatergic syn
Altered vesicular glutamate transporter distributions in the mouse cochlear nucleus following cochlear insult
Keywords: ABR; auditory brainstem response; ANF; auditory nerve fiber; ANOVA; analysis of variance; AVCN; anteroventral cochlear nucleus; CN; cochlear nucleus; DCN; dorsal cochlear nucleus; DCN1; molecular layer of the dorsal cochlear nucleus; DCN2; fusiform cell l
Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease
Keywords: HD; Huntington's disease; Rsk; 90-kDa ribosomal S6 kinase; AAV5; adeno-associated-virus 5; htt; huntingtin; BDNF; brain-derived neurotrophic factor; SRF; serum response factor; iEGs; immediate early-genes; GFP; green fluorescent protein; rpm; rotations pe
Transcranial theta-burst stimulation alters GLT-1 and vGluT1 expression in rat cerebellar cortex
Keywords: rTMS; Rat; Cerebellum; GLT-1; vGluT1; Glutathion;
Lipoic acid improves neuronal insulin signalling and rescues cognitive function regulating VGlut1 expression in high-fat-fed rats: Implications for Alzheimer's disease
Keywords: High-fat-diet; Insulin; Ketone bodies; Cognitive deficits; VGlut1;
The molecular physiology of the axo-myelinic synapse
Keywords: aCSF; artificial cerebrospinal fluid; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; AMPAR; AMPA receptor; ANOVA; (Analysis of variance); CNS; (Central nervous system); FCa.my; Ca2 +-dependent X-rhod-1 fluorescence from myelin; MBP; (myeli
Glutamatergic and central cholinergic dysfunction in the CA1, CA2 and CA3 fields on spatial learning and memory in chronic cerebral ischemia-Induced vascular dementia of rats
Keywords: AD; Alzheimer's disease; VaD; vascular dementia; CCI; Chronic Cerebral Global Ischemia; vGluT1; vesicular glutamate transporters type 1; vGluT2; vesicular glutamate transporters type 1; vGluT3; vesicular glutamate transporters type 3; vAChT; vesicular a
Aberrant excitatory rewiring of layer V pyramidal neurons early after neocortical trauma
Keywords: mEPSCs/sEPSCs; miniature and spontaneous excitatory postsynaptic currents; LSPS; laser scanning photostimulation; TBI; traumatic brain injury; GAP43; growth-associated protein-43; VGLUT1; vesicular glutamate transporter1; PSD95; postsynaptic density 95; V
Altered vesicular glutamate transporter expression in human temporal lobe epilepsy with hippocampal sclerosis
Keywords: VGLUT1; VGLUT2; VGLUT3; Human temporal lobe epilepsy; Hippocampal sclerosis;
Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents
Keywords: CB1 cannabinoid receptor; Frontal cortex; GABA; Glucocorticoid receptor; Glutamate; Presynaptic; 3Rs; Replacement, Refinement and Reduction of Animals in Research; 4-AP; 4-aminopyridine; ARRIVE; Animals in Research: Reporting In Vivo Experiments; CB1R(s)
Exercise prevents downregulation of hippocampal presynaptic proteins following olanzapine-elicited metabolic dysregulation in rats: Distinct roles of inhibitory and excitatory terminals
Keywords: ANCOVA; analysis of covariance; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; CA; Cornu Ammonis; cELISA; capture ELISA; dELISA; direct ELISA; DG; dentate gyrus; ELISA; enzyme-linked immunosorbent assay; GABA; gamma-aminobutyric aci
Connexin36 expression in major centers of the auditory system in the CNS of mouse and rat: Evidence for neurons forming purely electrical synapses and morphologically mixed synapses
Keywords: AVCN; anteroventral cochlear nucleus; CNIC; central nucleus of the inferior colliculus; CNS; central nervous system; Cx36; connexin36; DCIC; dorsal nucleus of the inferior colliculus; DCN; dorsal cochlear nucleus; DLL; dorsal nucleus of the lateral lemnis
Astrogliosis as a therapeutic target for neurodegenerative diseases
Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ATP; adenosine triphosphate; BB14®; nerve growth factor-like peptide; BDNF; brain-derived neurotrophic factor; Ca2+; calcium; CNS; central nervous system; COX-1/2; cyclooxygenase-1/2; EAAC1; ex
Mutant LRRK2 enhances glutamatergic synapse activity and evokes excitotoxic dendrite degeneration
Keywords: LRRK2; leucine rich repeat kinase 2; LRRK2-3HA; C-terminal 3Ã-hemagglutinin tagged LRRK2; cDNA; complementary deoxyribonucleic acid; mEPSC; miniature excitatory postsynaptic current; PD; Parkinson's disease; AMPA; (2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-
Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: Implications for neuropsychiatric diseases
Keywords: nAChR; nicotinic acetylcholine receptor; NMDAR; N-methyl-d-aspartate receptor; SR; serine racemase; VGLUT1; vesicular glutamate transporter 1; WT; wild-type; α7-KO; α7 nAChR null; α7 nicotinic acetylcholine receptor; Synaptic NMDA receptor; Extrasynapt
Cortical parvalbumin GABAergic deficits with α7 nicotinic acetylcholine receptor deletion: implications for schizophrenia
Keywords: nAChR; nicotinic acetylcholine receptor; PV; parvalbumin; SST; somatostatin; GAD65/67; glutamic acid decarboxylase 65/67; GABAAα1; α1 subunit of GABAA receptors; VGAT; vesicular GABA transporter; NMDAR; N-methyl-d-aspartate receptor; VGLUT1; vesicular g
Electron microscopy of primary cell cultures in solution and correlative optical microscopy using ASEM
Keywords: ASEM; atmospheric SEM; BM; bone marrow; BSE; backscattered electron; BEI; BSE imaging; Cbln1; cerebellin 1 precursor protein; CNS; central nervous system; CLEM; correlative light-electron microscopy; DC; dendritic cell; DIC; differential interference cont
Immunolocalization of the P2X4 receptor on neurons and glia in the mammalian retina
Keywords: BSA; bovine serum albumin; DAB; 3,3â²-diaminobenzidine; eATP; extracellular adenosine 5â²-triphosphate; GCL; ganglion cell layer; GFAP; anti-glial fibrillary acid protein; GFP; green fluorescent protein; GS; glutamine synthetase; HEPES; 2-[4-(2-Hydroxye