Serotonin transporter and memory

► The serotonin transporter (SERT) mediates memory, amnesia and anti-amnesic effects. ► AD and drugs like “ecstasy” decrease SERT expression and produce memory deficits. ► Evidence indicates that memory formation and amnesia affect the SERT expression. ► Memory and, in a major degree, amnesia make the SERT vulnerable to the effects of ecstasy. ► SERT is a reliable neural marker related to memory mechanisms, its alterations and treatment.