Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study

In obese children, actual weight and allometric weight are reasonable, convenient estimations of body fat to use for estimating vancomycin Vd and CL, respectively. However, these pharmacokinetic differences between obese children and those with normal weights are small and may not likely to be clinically relevant in dose variation.