Autoimmune biomarkers in glaucoma patients

► Changes in autoantibody profiles and IgG-antibody deposits in the retina occur in glaucoma. ► Elicited autoimmunity causes glaucomatous-like damage in an animal model. ► Antibodies of glaucoma patients influence proteins in retinal ganglion cells. ► Autoantibodies have a neuroprotective potential. ► Autoantibody patterns could be useful biomarkers for glaucoma diagnosis.