Drug transport via the intestinal peptide transporter PepT1

- The concept that PepT1 serves as a drug transporter has been further substantiated.
- Significant progress has been made on drugs such as cefadroxil and valacyclovir.
- Prodrugs of zanamivir, oseltamivir and didanosine have been developed.
- High affinity does not necessarily translate into actual drug translocation.