β-Glucan modulates the lipopolysaccharide-induced innate immune response in rat mammary epithelial cells

► Mammary epithelial cells as well as immune cells express pattern recognition receptors that play essential roles in mammary innate immunity. ► LPS induction of TLR4/MyD88/NF-κB in rat mammary epithelial cells. ► β-glucan activation of Dectin1/Syk attenuates pathway of LPS in rat mammary epithelial cells.