Changes in lymphocyte oxidant/antioxidant parameters after carbonyl and antioxidant exposure

► Effect of methylglyoxal/high glucose on lymphocyte oxidative parameters. ► Effect of astaxanthin with vitamin C on lymphocyte function. ► Methylglyoxal/high glucose did not promote oxidative stress in human lymphocytes. ► Astaxanthin with vitamin C proved to be a powerful antioxidant in human lymphocyte. ► The association of astaxanthin and vitamin C may be helpful to improve the immune function.