کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5833645 1122628 2012 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Trigonelline ameliorates diabetic hypertensive nephropathy by suppression of oxidative stress in kidney and reduction in renal cell apoptosis and fibrosis in streptozotocin induced neonatal diabetic (nSTZ) rats
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Trigonelline ameliorates diabetic hypertensive nephropathy by suppression of oxidative stress in kidney and reduction in renal cell apoptosis and fibrosis in streptozotocin induced neonatal diabetic (nSTZ) rats
چکیده انگلیسی
► Trigonelline (TG) is a plant hormone which is claimed to have antidiabetic and hypoglycemic activities. ► Oxidative stress and apoptosis play a central role in diabetic nephropathy. ► TG treatment ameliorates oxidative stress in mononuclear cells. ► Decreased apoptosis in renal cells confirmed the antiapoptotic role of trigonelline. ► Renal histology showed decreased tubular damage and fibrosis after TG treatment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Immunopharmacology - Volume 14, Issue 4, December 2012, Pages 740-748
نویسندگان
, , ,