کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5833855 1122634 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preparation and identification of a novel immunomodulator composed of muramyl dipeptide and anti-CD10 monoclonal antibody for treatment of minimal residual disease in acute leukemia children
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Preparation and identification of a novel immunomodulator composed of muramyl dipeptide and anti-CD10 monoclonal antibody for treatment of minimal residual disease in acute leukemia children
چکیده انگلیسی
► Targeted therapy is an useful approach for eliminating MRD to prevent tumor relapse. ► The immunomodulator (MDP-Ab) was constructed by coupling anti-CD10 MAb and MDP. ► On the basis of targeting function of MAb, MDP modulated to kill leukemia cells. ► Anti-CD10 MAb and MDP in the new immunoconjugate kept their own bioactivities. ► MDP-Ab immunomodulator could be a potentially useful drug to eradicate MRD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Immunopharmacology - Volume 11, Issue 9, September 2011, Pages 1211-1219
نویسندگان
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